Fast HPLC Method for the Determination of Piroxicam and its Application to Stability Study

@article{Panainte2017FastHM,
  title={Fast HPLC Method for the Determination of Piroxicam and its Application to Stability Study},
  author={Alina Diana Panainte and Mădălina Vieriu and Gladiola Ț{\^a}ntaru and Mihai Apostu and Nela Bibire},
  journal={Revista De Chimie},
  year={2017},
  volume={68},
  pages={701-706}
}
A fast and robust RP-HPLC isocratic method was developed for determination of piroxicam in bulk materials and pharmaceutical formulations. Optimum separation of piroxicam and stress induced degradation a product was achieved using a SB-C18 Eclipse column (150x4.6; 5μm). The mobile phase was a mixture of water: acetonitrile (50:50) with a flow rate of 0.5mL/min. The UV detection was performed at 360nm. The method was validated in accordance with the current ICH guidelines in terms of linearity… 
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