Fast, multi-frequency, and quantitative nanomechanical mapping of live cells using the atomic force microscope

@inproceedings{CartagenaRivera2015FastMA,
  title={Fast, multi-frequency, and quantitative nanomechanical mapping of live cells using the atomic force microscope},
  author={Alexander X Cartagena-Rivera and W Wang and Robert L. Geahlen and Arvind Raman},
  booktitle={Scientific reports},
  year={2015}
}
A longstanding goal in cellular mechanobiology has been to link dynamic biomolecular processes underpinning disease or morphogenesis to spatio-temporal changes in nanoscale mechanical properties such as viscoelasticity, surface tension, and adhesion. This requires the development of quantitative mechanical microscopy methods with high spatio-temporal resolution within a single cell. The Atomic Force Microscope (AFM) can map the heterogeneous mechanical properties of cells with high spatial… CONTINUE READING