Fasciola hepatica: tegumental changes induced in vitro by the deacetylated (amine) metabolite of diamphenethide.

@article{Fairweather1986FasciolaHT,
  title={Fasciola hepatica: tegumental changes induced in vitro by the deacetylated (amine) metabolite of diamphenethide.},
  author={Ian Fairweather and Herbert R. Anderson and Lawrence T. Threadgold},
  journal={Experimental parasitology},
  year={1986},
  volume={62 3},
  pages={
          336-48
        }
}
The effect of the deacetylated (amine) metabolite of diamphenethide (10 mugm/ml) on the tegument of Fasciola hepatica over a 24 hr period in vitro has been determined by means of transmission electron microscopy. In the tegumental syncytium, there is an initial accumulation of T2 secretory bodies at the apical surface (after 6 hr), together with increased exocytosis of secretory bodies and blebbing of the surface membrane. After 9 hr, the two surfaces of the fluke show different tegumental… CONTINUE READING

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