Fascin immunoreactivity for preoperatively predicting lymph node metastases in peripheral adenocarcinoma of the lung 3 cm or less in diameter.

@article{Choi2006FascinIF,
  title={Fascin immunoreactivity for preoperatively predicting lymph node metastases in peripheral adenocarcinoma of the lung 3 cm or less in diameter.},
  author={P. J. Choi and Doo Kyung Yang and Choon Hee Son and Kyung Eun Lee and Jae Ik Lee and Mee Sook Roh},
  journal={European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery},
  year={2006},
  volume={30 3},
  pages={538-42}
}
OBJECTIVE Fascin is an actin-bundling protein that induces cell membrane protrusions and increases the motility of normal and transformed epithelial cells. We evaluated the expression of fascin by performing immunohistochemistry to determine its role in the progression of small-size peripheral lung adenocarcinomas and to elucidate its utility as a preoperative novel therapeutic option. METHODS Immunohistochemistry for fascin was performed in 49 peripheral adenocarcinomas of <or= 3 cm in… CONTINUE READING
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World Health Organization International Histological Classification of Tumours. Pathology and genetics of tumors of the lung, pleura, thymus and heart

  • WD Travis, E Brambilla, HK Muller-Hermelink, CC. Harris
  • 2004
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