Fas2-ELISA in the detection of human infection by Fasciola hepatica.

  title={Fas2-ELISA in the detection of human infection by Fasciola hepatica.},
  author={Jos{\'e} Rolando Espinoza and Olga Timoteo and Patricia Herrera-Velit},
  journal={Journal of helminthology},
  volume={79 3},
Fasciola hepatica has recently emerged as a major pathogen of humans from reports on areas of endemicity and hyper-endemicity for fascioliasis. This situation is aggravated by the lack of standard assays for the screen diagnosis of F. hepatica infection in humans living in endemic areas. Our laboratory has developed an enzyme-linked immunosorbent assay (Fas2-ELISA) based on the capture of IgG antibody by a purified protein Fas2, which is an adult fluke cysteine proteinase. Fas2-ELISA exhibited… CONTINUE READING


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