Fas-mediated apoptosis in seven human prostate cancer cell lines: correlation with tumor stage.

@article{Hedlund1998FasmediatedAI,
  title={Fas-mediated apoptosis in seven human prostate cancer cell lines: correlation with tumor stage.},
  author={Tammy E Hedlund and Richard C. Duke and Mary S Schleicher and Gary J. Miller},
  journal={The Prostate},
  year={1998},
  volume={36 2},
  pages={92-101}
}
BACKGROUND Apoptosis, or programmed cell death, can be mediated through an endogenous signaling pathway that emanates from a cell surface receptor known as Fas. Although best recognized for its role in the immune system, recent studies have also suggested a role for Fas in mediating apoptosis in the murine prostate. Little is known, however, regarding the role of Fas-signaling in the human prostate, and if this signaling pathway is abrogated in the development of prostate cancer (PC). METHODS… CONTINUE READING

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