Fas ligand: receptor or ligand?

Abstract

In this review, we chronicle the discovery, biochemical characterization, and assignment of Fas (CD95) as receptor and Fas Ligand (FasL, CD95L) as ligand. We review the functional descriptions of the molecules as death-inducing receptor and ligand or as mediators of cell division and/or growth arrest. We suggest that bidirectional mediation of signals in… (More)
DOI: 10.1023/A:1009670802382

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