Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome.

@article{Albertine2002FasAF,
  title={Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome.},
  author={Kurt H. Albertine and Matthew F Soulier and Zhengming Wang and Akitoshi Ishizaka and Satoru Hashimoto and Guy A. Zimmerman and Michael A. Matthay and Lorraine B. Ware},
  journal={The American journal of pathology},
  year={2002},
  volume={161 5},
  pages={1783-96}
}
Apoptosis mediated by Fas/Fas ligand (FasL) interaction has been implicated in human disease processes, including pulmonary disorders. However, the role of the Fas/FasL system in acute lung injury (ALI) and in the acute respiratory distress syndrome (ARDS) is poorly defined. Accordingly, we investigated both the soluble and cellular expression of the Fas/FasL system in patients with ALI or ARDS. The major findings are summarized as follows. First, the soluble expression of the Fas/FasL system… CONTINUE READING

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