Fas and FasL expression in human adipose tissue are related to obesity , 1 insulin resistance and type 2 diabetes 2 3

Abstract

Context: Deletion of the death receptor Fas (CD95) in adipocytes of mice is associated with improved insulin sensitivity and reduced adipose tissue (AT) inflammation. Objective: Here we investigate the relationship of AT Fas with human obesity. Design and Methods: In paired samples of omental and sc AT from 256 lean and obese (including insulin-sensitive… (More)

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