Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover

@article{French1996FasAF,
  title={Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover},
  author={L. French and M. Hahne and I. Viard and G. Radlgruber and R. Zanone and K. Becker and C. M{\"u}ller and J. Tschopp},
  journal={The Journal of Cell Biology},
  year={1996},
  volume={133},
  pages={335 - 343}
}
  • L. French, M. Hahne, +5 authors J. Tschopp
  • Published 1996
  • Biology, Medicine
  • The Journal of Cell Biology
  • The cell surface receptor Fas (FasR, Apo-1, CD95) and its ligand (FasL) are mediators of apoptosis that have been shown to be implicated in the peripheral deletion of autoimmune cells, activation-induced T cell death, and one of the two major cytolytic pathways mediated by CD8+ cytolytic T cells. To gain further understanding of the Fas system., we have analyzed Fas and FasL expression during mouse development and in adult tissues. In developing mouse embryos, from 16.5 d onwards, Fas mRNA is… CONTINUE READING
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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 61 REFERENCES
    Expression of the Fas ligand in cells of T cell lineage.
    • 704
    Lethal effect of the anti-Fas antibody in mice
    • 1,948
    Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
    • 1,384
    Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)
    • 1,742
    • Highly Influential
    The Fas death factor
    • 4,200
    Fas ligand mediates activation-induced cell death in human T lymphocytes
    • 986
    • Open Access
    Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • 9,349
    • Open Access