Fas-activated apoptosis and apoptosis mediators in human trabecular meshwork cells.

@article{Agarwal1999FasactivatedAA,
  title={Fas-activated apoptosis and apoptosis mediators in human trabecular meshwork cells.},
  author={Rajnee Agarwal and Mihir Talati and Wendi S. Lambert and Abbot F. Clark and Steven E Wilson and Neeraj Agarwal and Robert James Wordinger},
  journal={Experimental eye research},
  year={1999},
  volume={68 5},
  pages={
          583-90
        }
}
A gradual loss of cells occurs within the human trabecular meshwork during normal aging and appears to be increased in patients with primary open-angle glaucoma. The exact mechanism by which cells are lost in either condition is not known, however phagocytosis, cell migration and cell death have been suggested. Apoptosis is one method by which cell death can occur. We have examined the modulators for apoptosis within the human trabecular meshwork using both cell lines and ex-vivo dissected… CONTINUE READING
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