Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocyte apoptosis.

Abstract

We wondered whether the apoptosis known to occur after UV-B irradiation might involve the Fas/Fas ligand (FasL) signaling pathway. We exposed PBLs from normal individuals, and also the Jurkat (E6-1) and U937 cell lines, to graded doses of UV-B irradiation and observed a prompt and marked increase in Fas expression at doses as low as 0.5 mJ/cm2. Increased… (More)

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@article{Caricchio1998FasFasLI, title={Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocyte apoptosis.}, author={Roberto Caricchio and Elizabeth A. Reap and Philip Cohen}, journal={Journal of immunology}, year={1998}, volume={161 1}, pages={241-51} }