Farm animals and inflammatory bowel disease: old MacDonald had poor hygiene.

The “hygiene hypothesis” suggests that a decrease in hildhood infection explains the rising prevalence of Telper type 1 (Th-1) and T-helper type 2 (Th-2) mediated utoimmune/inflammatory and allergic diseases (BMJ 989;299:1259 –1260). Specifically, in the inflammatory owel diseases (IBD), a lack of exposure to enteric pathoens early in childhood owing to… CONTINUE READING