Far-red/near-infrared fluorescence light-up probes for specific in vitro and in vivo imaging of a tumour-related protein

Abstract

As lysosomal protein transmembrane 4 beta (LAPTM4B) is an important biomarker for many solid tumours, development of small-molecule fluorescence light-up probes for detection and imaging of LAPTM4B proteins is particularly valuable. In this work, we reported the design and synthesis of a far-red/near-infrared (FR/NIR) fluorescence light-up probe DBT… (More)
DOI: 10.1038/srep23190

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