Far‐ultraviolet laser ablation of atherosclerotic lesions

@article{Linsker1984FarultravioletLA,
  title={Far‐ultraviolet laser ablation of atherosclerotic lesions},
  author={Ralph Linsker and Rangaswamy. Srinivasan and James J. Wynne and Daniel R. Alonso},
  journal={Lasers in Surgery and Medicine},
  year={1984},
  volume={4}
}
Far‐ultraviolet (far‐UV) (193 nm) laser radiation ablates arterial wall tissue, including noncalcified atherosclerotic lesions, with no apparent thermal damage to remaining tissue. This effect contrasts sharply with the thermal damage produced by visible‐wavelength laser irradiation. The mechanism by which far‐UV radiation interacts with tissue is predominantly photochemical rather than photothermal. Potential clinical applications include thsoe in which geometrically precise removal of tissue… 
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The motivation for the material presented in this chapter came initially from the development of a new generation of pulsed lasers for laser angioplasty, in which laser light delivered through a
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The flat slope of the etch depth curve for 193 nm suggests it will be a stable frequency when used clinically, and the most efficient cutting irradiance for each pulse appeared to be about 200 millijoules/sq cm.
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References

SHOWING 1-6 OF 6 REFERENCES
Ultraviolet-laser ablation of skin.
TLDR
In vitro, both wavelengths performed comparably, removing tissue precisely and cleanly, and leaving minimal thermal damage to the surrounding tissue, and the krypton-fluoride excimer laser beam at 248 nm has great potential as a surgical instrument.
Excimer laser surgery of the cornea.
Transluminal laser catheter angioplasty.
TLDR
The first transluminal laser angioplasty in animals is reported, using an Argon laser and a specialized coronary arterial catheter with a fiberoptic wave guide to treat intimal necrosis and loss of elastic tissue.
Self-developing photoetching of poly(ethylene terephthalate) films by far-ultraviolet excimer laser radiation
Radiation of 193‐nm (ArF excimer laser) wavelength can cause the etching of surfaces of poly(ethylene terephthalate) (PET) films in a controlled manner without any subsequent processing. Etch rates