Family with sequence similarity 13C (FAM13C) overexpression is an independent prognostic marker in prostate cancer

@article{Burdelski2017FamilyWS,
  title={Family with sequence similarity 13C (FAM13C) overexpression is an independent prognostic marker in prostate cancer},
  author={Christoph Burdelski and Laura Borcherding and Martina Kluth and Claudia Hube-Magg and Nathaniel Melling and Ronald Simon and Christina M{\"o}ller-Koop and P. Hern{\'a}ndez Weigand and Sarah Minner and Alexander Haese* and Hans Uwe Michl and Maria Christina Tsourlakis and Frank Jacobsen and Andrea Hinsch and Corinna Wittmer and Patrick Lebok and Stefan Steurer and Jakob R Izbicki and Guido Sauter and Till Krech and Franziska B{\"u}scheck and Till Sebastian Clauditz and Thorsten Schlomm and Waldemar Wilczak},
  journal={Oncotarget},
  year={2017},
  volume={8},
  pages={31494 - 31508}
}
FAM13C, a gene with unknown function is included in several mRNA signatures for prostate cancer aggressiveness. To understand the impact of FAM13C on prognosis and its relationship to molecularly defined subsets, we analyzed FAM13C expression by immunohistochemistry on a tissue microarray containing 12,400 prostate cancer specimens. Results were compared to phenotype, ERG status, genomic deletions of 3p, 5q, 6q and PTEN, and biochemical recurrence. FAM13C was detectable in cell nuclei of… 

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