Family of enhanced photoacoustic imaging agents for high-sensitivity and multiplexing studies in living mice.

@article{Zerda2012FamilyOE,
  title={Family of enhanced photoacoustic imaging agents for high-sensitivity and multiplexing studies in living mice.},
  author={Adam de la Zerda and Sunil Bodapati and Robert J. Teed and Salom{\'o}n Y May and Scott M. Tabakman and Zhuang Liu and Butrus T. Khuri-Yakub and Xiaoyuan Chen and Hongjie Dai and Sanjiv Sam Gambhir},
  journal={ACS nano},
  year={2012},
  volume={6 6},
  pages={
          4694-701
        }
}
Photoacoustic imaging is a unique modality that overcomes to a great extent the resolution and depth limitations of optical imaging while maintaining relatively high contrast. However, since many diseases will not manifest an endogenous photoacoustic contrast, it is essential to develop exogenous photoacoustic contrast agents that can target diseased tissue(s). Here we present a family of novel photoacoustic contrast agents that are based on the binding of small optical dyes to single-walled… CONTINUE READING

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