Family history, surgery, and APC mutation are risk factors for desmoid tumors in familial adenomatous polyposis: an international cohort study.

@article{Nieuwenhuis2011FamilyHS,
  title={Family history, surgery, and APC mutation are risk factors for desmoid tumors in familial adenomatous polyposis: an international cohort study.},
  author={Marry H. Nieuwenhuis and J{\'e}r{\'e}mie H Lefevre and Steffen B{\"u}low and Heikki J{\"a}rvinen and Lucio Bertario and Solen Kern{\'e}is and Yann R Parc and Hans F. A. Vasen},
  journal={Diseases of the colon and rectum},
  year={2011},
  volume={54 10},
  pages={1229-34}
}
BACKGROUND Ability to identify patients with familial adenomatous polyposis who have a high risk of developing desmoid tumors may affect decisions in clinical practice. OBJECTIVES Our aim was to assess several risk factors for desmoid tumor development in an international cohort of patients with familial adenomatous polyposis and to evaluate the clinical relevance of risk factors. DESIGN This was a retrospective cohort study. SETTING AND PATIENTS Polyposis registries in The Netherlands… CONTINUE READING
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