Family-based study of DRD2 alleles in alcohol and drug dependence.

@article{Blomqvist2000FamilybasedSO,
  title={Family-based study of DRD2 alleles in alcohol and drug dependence.},
  author={Ola Blomqvist and Joel Gelernter and Henry R. Kranzler},
  journal={American journal of medical genetics},
  year={2000},
  volume={96 5},
  pages={
          659-64
        }
}
Numerous case-control studies have addressed the hypothesis that variant alleles of the dopamine D2 receptor gene (DRD2) increase the liability for alcohol and/or drug dependence, and both positive and negative results have been reported. Because population frequencies of these alleles vary considerably, the conflicting results could be due to population stratification bias. Using the transmission disequilibrium test, the present study examined linkage disequilibrium of alcohol and drug (opioid… CONTINUE READING

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The dopamine system and alcohol dependence

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  • 2014
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