Family-based association studies of monoaminergic gene polymorphisms among North Indians with schizophrenia

@article{Semwal2001FamilybasedAS,
  title={Family-based association studies of monoaminergic gene polymorphisms among North Indians with schizophrenia},
  author={Prachi Semwal and Suman Prasad and Triptish Bhatia and Smita N. Deshpande and Julie A. Wood and Vishwajit L. Nimgaonkar and B. K. Thelma},
  journal={Molecular Psychiatry},
  year={2001},
  volume={6},
  pages={220-224}
}
Associations between schizophrenia and four candidate genes were tested among Indian patients with schizophrenia and their parents (DSM-IV criteria, n = 179 families). Polymorphisms within the genes encoding the serotonin 2A receptor (HT2A), tryptophan hydroxylase (TPH), catechol-O-methyl transferase (COMT) and dopamine transporter (DAT) were thus investigated. Two polymorphisms each were analyzed at HT2A and TPH, enabling haplotype-based analyses using the transmission disequilibrium test (TDT… CONTINUE READING
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