Family-based association analysis of S100A8 genetic polymorphisms with aggressive periodontitis.

@article{Ren2009FamilybasedAA,
  title={Family-based association analysis of S100A8 genetic polymorphisms with aggressive periodontitis.},
  author={Xiu-yun Ren and Li Xu and Huan Meng and Hong Zhao and Ruifang Lu and Zhi Bin Chen and Xiang Hui Feng and Dong Hong Shi and Li Zhang and Ye Tian},
  journal={Journal of periodontal research},
  year={2009},
  volume={44 2},
  pages={184-92}
}
BACKGROUND AND OBJECTIVE It is known that S100A8, a member of the S100 calcium-binding protein family, is associated with inflammatory diseases, including periodontitis. Our previous population-based study found an association between two polymorphisms, rs3795391 (A > G) and rs3806232 (A > G), in the upstream region of the S100A8 gene and aggressive periodontitis (AgP) in Chinese people. Based on those results, this investigation set out to analyze and corroborate whether the association also… CONTINUE READING
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