Family- and population-based association studies of monoamine oxidase A and autism spectrum disorders in Korean.

@article{Yoo2009FamilyAP,
  title={Family- and population-based association studies of monoamine oxidase A and autism spectrum disorders in Korean.},
  author={Hee-jeong Yoo and Seong Kyu Lee and Mira Park and In Hee Cho and Seung Hee Hyun and Je Chul Lee and So Young Yang and Soon Ae Kim},
  journal={Neuroscience research},
  year={2009},
  volume={63 3},
  pages={172-6}
}
Monoamine oxidase A gene (MAOA) has been thought to be a candidate gene implicated in autism spectrum disorder (ASD). This study evaluates the relationship between ASDs and MAOA markers (i.e., uVNTR and four single nucleotide polymorphisms (SNPs)) in 151 Korean family trios with children diagnosed with ASDs, and 193 unrelated Korean controls. The result of case-control global haplotype analysis also showed a statistically significant difference in haplotype frequencies between ASD patients and… CONTINUE READING

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