Family Coronaviridae

  title={Family Coronaviridae},
  author={Susan L Payne},
  pages={149 - 158}
  • S. Payne
  • Published 1 September 2017
  • Biology
  • Viruses

Figures and Tables from this paper

Basic Virology and Pathophysiology of COVID-19
This chapter presents a detailed description of the basic virology and pathophysiology of SARS-CoV-2, a single-stranded RNA virus containing a genome of approximately 30,000 base pairs that is a zoonotic virus that has somehow jumped to humans.
The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing
Origin and Evaluation of Pathogenic Coronavirus: A Literature Review
Quite a few coronaviruses phylogenetically linked with SARS-CoV were identified in bats from entirely different provinces in China and also from European, African, and Southeast Asian countries, so the genesis of coronavirus is yet under controversy and needs more attention.
Coronaviruses: a review of their properties and diversity
The high prevalence of coronavirus in domestic and wild animals, especially bats and birds, and the propensity for their genomes to undergo mutation and recombination may lead to emergence of new coronaviruses that could pose a serious threat to human and animal health.
Nidoviruses of Fish and Crustaceans
Discovery of a novel nidovirus in cattle with respiratory disease.
The discovery and genetic characterization of a novel virus present in cattle with respiratory disease and analysis of polyprotein 1ab revealed that this virus shares the highest homology with the recently described python-borne nidoviruses, but does not encode the NendoU or O-MT domains that are present in other viruses within the family Coronaviridae.
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats
A new member of alphaCoV (BtCoV/Rh/YN2012) in bats with unique genome features is described and functional analysis showed ORF4a protein can activate IFN-β production, whereas ORF3a can regulate NF-κB production, which expands the knowledge on the genetic diversity of bat coronaviruses.
Characterization of a bafinivirus exoribonuclease activity.
WBV ExoN was revealed to be most active on double-stranded RNA substrates containing one or two non-paired 3'-terminal nucleotides, supporting its presumed role in increasing the fidelity of the bafinivirus RNA-dependent RNA polymerase.
Knowing our Rival–Coronaviridae: The Virus Family
This chapter will describe the biological nature of viruses belonging to the Coronaviridae family, as well as their clinical characteristics and diagnostics, in order to understand their disease-causing pattern and the efficacy of vaccination in mitigating the worst outcomes of the disease.


Emergence of Pathogenic Coronaviruses in Cats by Homologous Recombination between Feline and Canine Coronaviruses
Observations suggest that type II FCoV emerged inside the cat body and is unable to readily spread among cats, indicating that these recombination events for emergence of pathogenic coronaviruses occur frequently.