Family Coronaviridae

  title={Family Coronaviridae},
  author={Family Coronaviridae},
  booktitle={Virus Taxonomy},
RNA structure analysis of alphacoronavirus terminal genome regions
Novel divergent nidovirus in a python with pneumonia.
Analysis of genome organization and phylogenetic analysis of polyprotein 1ab suggests that this virus belongs to the subfamily Torovirinae, and results of this study provide novel insights into the genetic diversity within the order Nidovirales.
Leader sequences of coronavirus are altered during infection.
It is demonstrated that the replication intermediates of minus strand of subgenomic RNA (sgRNA) can be readily recovered from SARS-CoV infected cells and a novel sgmRNA (M-1) was identified as a short version of membrane (M) gene, implying that the leader sequence of coronavirus might be unstable and leader alterations during SARS -CoV transmission in humans might have negative impact on its viral infectivity.
Coronaviruses in Aquatic Organisms
Genomic characterization of seven distinct bat coronaviruses in Kenya
Gamma and Deltacoronaviruses in quail and pheasants from Northern Italy1
RNA‐dependent RNA polymerase (RdRp) analyses showed the susceptibility of quail also to Deltacoronavirus, suggesting that quail and pheasant avian coronaviruses share spike genes identical to chicken IBV spike genes and quail might host Deltacanavirus.
Complete genomic sequence of the coronavirus transmissible gastroenteritis virus SHXB isolated in China
Phylogenetic analysis showed that TGEV SHXB was closely related to the Purdue strains and shared a common ancestor with the Miller strains as well as strain PRCV-ISU-1.
Coronavirus cis-Acting RNA Elements


Characterization of White Bream Virus Reveals a Novel Genetic Cluster of Nidoviruses
Analysis of the nucleotide sequence, organization, and expression of the 26.6-kb genome provided conclusive evidence for a phylogenetic relationship between WBV and nidoviruses and appeals for a more extensive characterization of nonmammalian nidviruses to better understand the evolution of these largest known RNA viruses.
Nidovirus transcription: how to make sense...?
Nidovirus transcription mechanisms are compared, the experimental systems used are critically assessed and, in particular, the impact of recently developed reverse genetic systems is discussed.
Coronavirus Diversity, Phylogeny and Interspecies Jumping
The present evidence supports that bat coronaviruses are the gene pools of group 1 and 2 coronaviraluses, whereas bird coronavirus are the genes of group 3 coronavIRuses.
Discovery of the First Insect Nidovirus, a Missing Evolutionary Link in the Emergence of the Largest RNA Virus Genomes
Rooted phylogenetic inference by Bayesian and Maximum Likelihood methods indicates that NDiV clusters with roniviruses and that its branch diverged from large nidoviruses early after they split from small nidviruses, a hypothesis that provides evolutionary support using comparative genomics involving the newly discovered first insect-borne ndovirus.
Cryo-electron tomography of mouse hepatitis virus: Insights into the structure of the coronavirion
A general model for the structure of the coronavirion is proposed in which the own and published observations are combined and all the general features and global architecture observed for MHV are confirmed.
Biochemical aspects of coronavirus replication and virus-host interaction.
Both viral and cellular proteins are required for replication and transcription, and the role of selected proteins is addressed.
A Contemporary View of Coronavirus Transcription
The hallmark of coronavirus transcription is the production of multiple subgenomic mRNAs that contain sequences corresponding to both ends of the genome.
Coronaviruses post-SARS: update on replication and pathogenesis
This Review focuses on recent advances in the understanding of the mechanisms of coronavirus replication, interactions with the host immune response and disease pathogenesis and the recent identification of numerous novel coronaviruses.
Coronaviruses: Molecular and Cellular Biology
  • J. Leibowitz
  • Biology, Medicine
    Emerging Infectious Diseases
  • 2008
Coronaviruses: Molecular and Cellular Biology is published as a monograph for the first time in a systematic fashion and aims to provide a scaffolding for future studies of these enigmatic viruses.