Family-Based Association Analysis of Serotonin Genes in Pathological Gambling Disorder: Evidence of Vulnerability Risk in the 5HT-2A Receptor Gene

@article{Wilson2012FamilyBasedAA,
  title={Family-Based Association Analysis of Serotonin Genes in Pathological Gambling Disorder: Evidence of Vulnerability Risk in the 5HT-2A Receptor Gene},
  author={David Wilson and Daniela Sabbatini da Silva Lobo and Hermano Tavares and Valentim Gentil and Homero Vallada},
  journal={Journal of Molecular Neuroscience},
  year={2012},
  volume={49},
  pages={550-553}
}
Pathological gambling (PG) has become a growing public health problem in many countries around the world. PG is an impulse control disorder and its behavior and psychopathology present similarities with substance abuse disorders. Evidence from twin studies supports a significant genetic predisposition to PG, but the precise genetic loci still remain unclear. The present study investigates the allele and genotype distribution of polymorphisms of the serotonin transporter, serotonin receptor 1B… CONTINUE READING
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