Families of ion channels with two hydrophobic segments.

  title={Families of ion channels with two hydrophobic segments.},
  author={R Alan North},
  journal={Current opinion in cell biology},
  volume={8 4},
  • R Alan North
  • Published 1996 in Current opinion in cell biology
The family of epithelial sodium channels and nematode degenerins has expanded recently to include a member found only in brain, and another that functions in molluscs as a ligand-gated channel. A new gene family of mammalian ATP-gated channels has been discovered; one of its seven members plays a role in the lysis of macrophages. The mechanosensitive channel of bacteria has emerged as the simplest form of a channel protein subunit with two hydrophobic domains. 

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