Families of Proteins Forming Transmembrane Channels

@article{Saier2000FamiliesOP,
  title={Families of Proteins Forming Transmembrane Channels},
  author={Jr. M.H. Saier},
  journal={The Journal of Membrane Biology},
  year={2000},
  volume={175},
  pages={165-180}
}
Channel-forming proteins/peptides fall into over 100 currently recognized families, most of which are restricted to prokaryotes or eukaryotes, but a few of which are ubiquitous. These proteins fall into three major currently recognized classes: (i) α-helix-type channels present in bacterial, archaeal and eukaryotic cytoplasmic and organellar membranes, (ii) β-barrel-type porins present in the outer membranes of Gram-negative bacterial cells, mitochondria and chloroplasts, and (iii) protein… CONTINUE READING

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