Familiality and clinical outcomes of sleep disturbances in major depressive and bipolar disorders.

@article{Lai2014FamilialityAC,
  title={Familiality and clinical outcomes of sleep disturbances in major depressive and bipolar disorders.},
  author={Yin-Chieh Lai and Ming-Chyi Huang and Hsi-Chung Chen and M Z Lu and Yi-Hang Chiu and Winston Wu-Dien Shen and Ru-Band Lu and Po-Hsiu Kuo},
  journal={Journal of psychosomatic research},
  year={2014},
  volume={76 1},
  pages={61-7}
}
OBJECTIVE Sleep disturbances are frequently observed in major depressive (MDD) and bipolar disorder (BD). This study reported sleep profiles of patients and their relatives versus controls, and examined the familiality of sleep features in mood disorder families. We also evaluated the influences of sleep disturbance on patients' quality of life (QOL), functional impairment, and suicidality. METHODS We recruited 363 BD and 157 MDD patients, 521 first-degree relatives, and 235 healthy controls… CONTINUE READING