Familial transmission and minimal sequence variability of human T-lymphotropic virus type I (HTLV-I) in Zaire.

@article{Liu1994FamilialTA,
  title={Familial transmission and minimal sequence variability of human T-lymphotropic virus type I (HTLV-I) in Zaire.},
  author={H. F. Liu and Anne Mieke Vandamme and K Kazadi and Herwig Carton and Jan Desmyter and Patrick Goubau},
  journal={AIDS research and human retroviruses},
  year={1994},
  volume={10 9},
  pages={1135-42}
}
Our group previously reported a strong familial clustering of HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Zaire, suggesting a familial transmission of the virus together with the presence of cofactors. In the present study among 84 relatives of 16 HTLV-I-positive or HAM/TSP index cases, we found that all 15 seropositive children had a seropositive mother and that all 15 children with a seropositive father but a seronegative mother were seronegative. Lymphocytes of 17… CONTINUE READING

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Our group previously reported a strong familial clustering of HTLV - I - associated myelopathy / tropical spastic paraparesis ( HAM / TSP ) in Zaire , suggesting a familial transmission of the virus together with the presence of cofactors .
Our group previously reported a strong familial clustering of HTLV - I - associated myelopathy / tropical spastic paraparesis ( HAM / TSP ) in Zaire , suggesting a familial transmission of the virus together with the presence of cofactors .
Comparison of the LTR sequences of the two families with other HTLV - I strains from different geographical regions shows that the Zairean HTLV - I strains form a separate cluster.(ABSTRACT TRUNCATED AT 250 WORDS ) .
Our group previously reported a strong familial clustering of HTLV - I - associated myelopathy / tropical spastic paraparesis ( HAM / TSP ) in Zaire , suggesting a familial transmission of the virus together with the presence of cofactors .
Our group previously reported a strong familial clustering of HTLV - I - associated myelopathy / tropical spastic paraparesis ( HAM / TSP ) in Zaire , suggesting a familial transmission of the virus together with the presence of cofactors .
Our group previously reported a strong familial clustering of HTLV - I - associated myelopathy / tropical spastic paraparesis ( HAM / TSP ) in Zaire , suggesting a familial transmission of the virus together with the presence of cofactors .
Our group previously reported a strong familial clustering of HTLV - I - associated myelopathy / tropical spastic paraparesis ( HAM / TSP ) in Zaire , suggesting a familial transmission of the virus together with the presence of cofactors .
The HTLV - I long terminal repeat ( LTR ) of these 10 individuals , related in the first to the fourth degree , was amplified and sequenced .
Comparison of the LTR sequences of the two families with other HTLV - I strains from different geographical regions shows that the Zairean HTLV - I strains form a separate cluster.(ABSTRACT TRUNCATED AT 250 WORDS ) .
Comparison of the LTR sequences of the two families with other HTLV - I strains from different geographical regions shows that the Zairean HTLV - I strains form a separate cluster.(ABSTRACT TRUNCATED AT 250 WORDS ) .
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