Familial subepithelial corneal amyloidosis--a lactoferrin-related amyloidosis.

@article{Klintworth1997FamilialSC,
  title={Familial subepithelial corneal amyloidosis--a lactoferrin-related amyloidosis.},
  author={Gordon K. Klintworth and Zuzana Valnickova and R A Kielar and Keith H. Baratz and Robert A. J. Campbell and Jan J Enghild},
  journal={Investigative ophthalmology & visual science},
  year={1997},
  volume={38 13},
  pages={
          2756-63
        }
}
PURPOSE To isolate the protein that collects in increased amounts beneath the corneal epithelium in familial subepithelial corneal amyloidosis (FSCA), also known as gelatinous droplike corneal dystrophy, and to identify it by N-terminal amino acid sequencing. METHODS Peptides resulting from pepsin digestion of a unique protein isolated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis from frozen tissue from two corneas with FSCA were purified by high-pressure liquid chromatography… CONTINUE READING

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