Familial predisposition to monoclonal gammopathy of unknown significance, Waldenström's macroglobulinemia, and multiple myeloma.

@article{Ogmundsdottir2009FamilialPT,
  title={Familial predisposition to monoclonal gammopathy of unknown significance, Waldenstr{\"o}m's macroglobulinemia, and multiple myeloma.},
  author={Helga Margret Ogmundsdottir and Helga Einarsd{\'o}ttir and Hl{\'i}f Steingr{\'i}msd{\'o}ttir and Vilhelm{\'i}na Haraldsd{\'o}ttir},
  journal={Clinical lymphoma & myeloma},
  year={2009},
  volume={9 1},
  pages={27-9}
}
The medical literature contains reports of around 130 families with two or more cases of MM, MGUS, or WM. An Icelandic family with multiple cases of MGUS, WM, and lymphoma was first described in 1978. In vitro testing of peripheral blood lymphocytes revealed increased production of immunoglobulins in response to poke-weed mitogen in 10 out of 35 family… CONTINUE READING