Familial orthostatic tachycardia due to norepinephrine transporter deficiency.

  title={Familial orthostatic tachycardia due to norepinephrine transporter deficiency.},
  author={David P. Robertson and Nancy L Flattem and Tahir Tellioglu and Robert Carson and Emily M. Garland and J. Richard Shannon and Jens Jordan and Giris Jacob and Randy D. Blakely and Italo Biaggioni},
  journal={Annals of the New York Academy of Sciences},
UNLABELLED Orthostatic intolerance (OI) or postural tachycardia syndrome (POTS) is a syndrome primarily affecting young females, and is characterized by lightheadedness, palpitations, fatigue, altered mentation, and syncope primarily occurring with upright posture and being relieved by lying down. There is typically tachycardia and raised plasma norepinephrine levels on upright posture, but little or no orthostatic hypotension. The pathophysiology of OI is believed to be very heterogeneous… CONTINUE READING
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