Familial neonatal isolated cardiomyopathy caused by a mutation in the flavoprotein subunit of succinate dehydrogenase

@article{Levitas2010FamilialNI,
  title={Familial neonatal isolated cardiomyopathy caused by a mutation in the flavoprotein subunit of succinate dehydrogenase},
  author={Aviva Levitas and Emad Muhammad and Gali Harel and Ann Saada and Vered Chalifa Caspi and Esther Manor and John C. Beck and Val Sheffield and Ruti Parvari},
  journal={European Journal of Human Genetics},
  year={2010},
  volume={18},
  pages={1160-1165}
}
Cardiomyopathies are common disorders resulting in heart failure; the most frequent form is dilated cardiomyopathy (DCM), which is characterized by dilatation of the left or both ventricles and impaired systolic function. DCM causes considerable morbidity and mortality, and is one of the major causes of sudden cardiac death. Although about one-third of patients are reported to have a genetic form of DCM, reported mutations explain only a minority of familial DCM. Moreover, the recessive… CONTINUE READING

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