Familial multiple cervical paragangliomas: report of a kindred and review of the literature.

@article{Sobol1990FamilialMC,
  title={Familial multiple cervical paragangliomas: report of a kindred and review of the literature.},
  author={S M Sobol and Jacque Dailey},
  journal={Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery},
  year={1990},
  volume={102 4},
  pages={382-90}
}
Heredofamilial paragangliomas account for less than 10% of those arising in the head and neck. Multiplicity, multicentricity, and bilaterality is roughly three times more common than in the spontaneous variety. Not unlike other hereditary neuroendocrine tumor syndromes, familial paragangliomas appear to follow an autosomal dominant transmission, with variable penetrance and expressivity. This article describes a surgical experience with nine bilateral, multicentric cervical paragangliomas (7… CONTINUE READING

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