Familial migraine: exclusion of the susceptibility gene from the reported locus of familial hemiplegic migraine on 19p.

@article{Hovatta1994FamilialME,
  title={Familial migraine: exclusion of the susceptibility gene from the reported locus of familial hemiplegic migraine on 19p.},
  author={Iiris Hovatta and Mikko Kallela and Markus F{\"a}rkkil{\"a} and L. Peltonen},
  journal={Genomics},
  year={1994},
  volume={23 3},
  pages={707-9}
}
Genetic isolates are highly useful in analyses of the molecular background of complex diseases since the enrichment of a limited number of predisposing genes can be predicted in representative families or in specific geographical regions. It has been suggested that the pathophysiology and etiology of familial hemiplegic migraine (FHM) and typical migraine with aura are most probably the same. Recent assignment of FHM locus to chromosome 19p in two French families makes it now possible to test… CONTINUE READING

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