Familial mediterranean fever: revisiting an ancient disease

@article{Ozen2003FamilialMF,
  title={Familial mediterranean fever: revisiting an ancient disease},
  author={Seza Ozen},
  journal={European Journal of Pediatrics},
  year={2003},
  volume={162},
  pages={449-454}
}
  • S. Ozen
  • Published 2003
  • Medicine
  • European Journal of Pediatrics
Familial Mediterranean fever (FMF) is an auto-inflammatory disease characterised by periodic attacks of fever and serositis. Recent genetic and epidemiological research have highlighted the importance of this disease. FMF is the most frequent periodic fever syndrome and is transmitted in an autosomal recessive fashion. The disease is caused by mutations in the gene on the short arm of chromosome 16, coding for the protein "pyrin". Pyrin is mainly expressed in neutrophils and monocytes and is… Expand
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