Familial malignant melanoma of the uvea and p53: a Victorian detective story.

@article{Jay1993FamilialMM,
  title={Familial malignant melanoma of the uvea and p53: a Victorian detective story.},
  author={Marcelle Jay and Alison C. E. McCartney},
  journal={Survey of ophthalmology},
  year={1993},
  volume={37 6},
  pages={457-62}
}
In 1905, Parsons first described a family with a history of four generations with uveal melanoma associated with breast cancer. The family history has now been brought up to date using genealogical sources to determine the origin of this family which was traced to the East End of London in the early 19th century. In addition, immunohistochemical… CONTINUE READING