Familial inappropriate TSH secretion: evidence suggesting a dissociated pituitary resistance to T3 and T4.


The study of pituitary thyroid relationships of a 40-year-old woman, suffering from recurrent goiter, is presented. The characteristics of this case were the following: i) constant hyperthyrotropinemia (range 8.2 to 29 micro u/ml) despite high thyroid hormone levels (mean total T4:13.4 microgram/dl; mean total T3:255 ng/dl) and clinical euthyroidism; ii… (More)


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