Familial hypercholesterolemia in children

@article{Rodenburg2004FamilialHI,
  title={Familial hypercholesterolemia in children},
  author={J. Rodenburg and M. N. Vissers and A. Wiegman and M. Trip and H. D. Bakker and J. Kastelein},
  journal={Current Opinion in Lipidology},
  year={2004},
  volume={15},
  pages={405-411}
}
Purpose of this review This review provides an update on recent advances in the diagnosis and management of children with familial hypercholesterolemia. Recent findings A large cross-sectional cohort study of paediatric familial hypercholesterolemia demonstrated that affected children had a 5-fold more rapid increase of carotid arterial wall intima-media thickness during childhood years than their affected siblings. This faster progression led to a significant deviation in terms of intima-media… Expand
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45 Citations

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Endothelial Dysfunction, But Not Structural Atherosclerosis, Is Evident Early in Children With Heterozygous Familial Hypercholesterolemia
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Portuguese Familial Hypercholesterolemia Study: presentation of the study and preliminary results.
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Detection of familial hypercholesterolemia in a cohort of children with hypercholesterolemia: results of a family and DNA-based screening.
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Endothelial activation, inflammation and premature atherosclerosis in children with familial dyslipidemia.
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Long-Term Follow-Up of Statin Treatment in a Cohort of Children with Familial Hypercholesterolemia
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Management of familial hypercholesterolemia in children and young adults: consensus paper developed by a panel of lipidologists, cardiologists, paediatricians, nutritionists, gastroenterologists, general practitioners and a patient organization.
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