Familial clustering of Barrett's esophagus and esophageal adenocarcinoma in a European cohort.

@article{Verbeek2014FamilialCO,
  title={Familial clustering of Barrett's esophagus and esophageal adenocarcinoma in a European cohort.},
  author={Romy E. Verbeek and Lisanne F. Spittuler and Anique Peute and Martijn G H van Oijen and Fiebo J. W. ten Kate and J. Reinoud Vermeijden and Ardi H Oberndorff and Jantine W van Baal and Peter D Siersema},
  journal={Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association},
  year={2014},
  volume={12 10},
  pages={
          1656-63.e1
        }
}
BACKGROUND & AIMS Up to 7% of cases of Barrett's esophagus (BE) or esophageal adenocarcinoma (EAC) in the United States occur in family clusters. We identified first-degree and second-degree relatives of patients with BE and EAC to determine the extent of familial clustering in a European cohort and studied differences between familial and nonfamilial cases. METHODS A questionnaire was sent to all patients diagnosed with BE or EAC from 2000-2011 at 3 hospitals in the Netherlands (n = 838… CONTINUE READING
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