Familial autosomal dominant cortico-basal degeneration with the P301S mutation in the tau gene: an example of phenotype variability

@article{Casseron2005FamilialAD,
  title={Familial autosomal dominant cortico-basal degeneration with the P301S mutation in the tau gene: an example of phenotype variability},
  author={Wilfrid Casseron and Prof. J. P. Azulay and Eric Guedj and J. L. Gastaut and J. Pouget},
  journal={Journal of Neurology},
  year={2005},
  volume={252},
  pages={1546-1548}
}
Sirs: A subset of familial frontotemporal dementia with Parkinsonism is caused by mutations in the tau gene on chromosome 17 (FTDP17) [3].Among those mutations, P301S mutation has been reported in only four families [1, 2, 4, 6], and in a recent issue of this journal, three cases of FTDP-17 from a Jewish-Algerian family have already been reported by Lossos… CONTINUE READING