Familial associations of rheumatoid arthritis with autoimmune diseases and related conditions.

@article{Hemminki2009FamilialAO,
  title={Familial associations of rheumatoid arthritis with autoimmune diseases and related conditions.},
  author={Kari Hemminki and Xinjun Li and Jan Sundquist and Kristina Sundquist},
  journal={Arthritis and rheumatism},
  year={2009},
  volume={60 3},
  pages={661-8}
}
OBJECTIVE In the era of genome-wide association studies, familial risks are used to estimate disease heritability and the likelihood of candidate-gene identification. This study was undertaken to estimate associations of rheumatoid arthritis (RA) with any of 33 autoimmune diseases and related conditions among parents and offspring, singleton siblings, twins, and spouses. METHODS The Multigeneration Register in Sweden was used as a reliable source of information on Swedish families throughout… CONTINUE READING

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