Familial and sporadic human renal cell carcinoma: evidence against a double-loss mechanism of carcinogenesis.

Abstract

It has been speculated that renal cell carcinoma (RCC) is an example of a double-loss mutation. We analyzed the age distribution of 71 cases of familial RCC and of 11 population-based cancer registries [German Democratic Republic, Denmark, Finland, Norway, Sweden, U.S.A. Whites, U.S.A. Blacks, Miyagi and Osaka Prefectures (Japan), Hong Kong, and Israeli… (More)

Topics

Cite this paper

@article{Stein1995FamilialAS, title={Familial and sporadic human renal cell carcinoma: evidence against a double-loss mechanism of carcinogenesis.}, author={Wendy Stein and Andreas Stein}, journal={Journal of clinical epidemiology}, year={1995}, volume={48 6}, pages={767-77} }