Familial amyloidotic polyneuropathy: ocular manifestations with clinicopathological observation.

@article{Futa1984FamilialAP,
  title={Familial amyloidotic polyneuropathy: ocular manifestations with clinicopathological observation.},
  author={Ryusuke Futa and Ken ichi Inada and Hisayuki Nakashima and Hiroyuki Baba and Yasuyuki Kojima and Ryoichi Okamura and Shukuro Araki},
  journal={Japanese journal of ophthalmology},
  year={1984},
  volume={28 3},
  pages={289-98}
}
Clinical findings of ocular involvement in two patients with familial amyloidotic polyneuropathy are described. Both cases revealed irregular pupillary margin, white membranous material on the pupillary border and on the lens surface. Open-angle glaucoma was found in one case, and ocular hypertension in the other. Histopathological examination of the tissues obtained during trabeculectomy in Case 1 revealed a large amount of amyloid substance around the vessels of the conjunctiva and the iris… CONTINUE READING