Familial amyloid polyneuropathy: a clinico-pathologic study.


UNLABELLED In familial amyloid polyneuropathy (FAP), destruction of nerve fibres is related to accumulation of mutated transthyretin (mTTR) derived amyloid deposits (AD) in the endoneurium. Liver transplantation (LT), which removes the main source of mTTR, does not prevent deterioration of the clinical condition in all recipients. MATERIAL AND METHODS We… (More)
DOI: 10.1016/j.jns.2009.05.001