Familial aggregation in Crohn's disease: increased age-adjusted risk and concordance in clinical characteristics.

@article{Peeters1996FamilialAI,
  title={Familial aggregation in Crohn's disease: increased age-adjusted risk and concordance in clinical characteristics.},
  author={Miek Peeters and H Nevens and Filip Baert and Martin I. Hiele and Anne-Marie de Meyer and Robert F M H Vlietinck and P. R. Rutgeerts},
  journal={Gastroenterology},
  year={1996},
  volume={111 3},
  pages={597-603}
}
BACKGROUND & AIMS Because the mode of Crohn's disease inheritance is unknown, age-adjusted risk estimates and knowledge of disease characteristics will aid genetic counseling and modeling. The aim of this study is to determine the prevalence of familial occurrence of inflammatory bowel disease in first-degree relatives of patients with Crohn's disease and estimate their age-adjusted risks. It also evaluates agreement in disease characteristics between generations within families with a history… CONTINUE READING

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