• DOI:10.1038/12502
Corpus ID: 14809619

Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans

@article{Jones1999FamilialAS,
  title={Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans},
  author={C. R. Jones and S. Campbell and Stephanie E. Zone and Fred Cooper and Alison DeSano and P. J. Murphy and B. Jones and L. Czajkowski and Louis J. Pt{\vc}ek},
  journal={Nature Medicine},
  year={1999},
  volume={5},
  pages={1062-1065}
}

• C. R. Jones, S. Campbell, +6 authors Louis J. Ptček
• Published 1999
• Biology, Medicine
• Nature Medicine

Biological circadian clocks oscillate with an approximately 24-hour period, are ubiquitous, and presumably confer a selective advantage by anticipating the transitions between day and night. The circadian rhythms of sleep, melatonin secretion and body core temperature are thought to be generated by the suprachiasmatic nucleus of the hypothalamus, the anatomic locus of the mammalian circadian clock. Autosomal semi-dominant mutations in rodents with fast or slow biological clocks (that is, short… Expand

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