Familial Risk and Heritability of Colorectal Cancer in the Nordic Twin Study of Cancer.


BACKGROUND & AIMS We analyzed data from twins to determine how much the familial risk of colorectal cancer can be attributed to genetic factors vs environment. We also examined whether heritability is distinct for colon vs rectal cancer, given evidence of distinct etiologies. METHODS Our data set included 39,990 monozygotic and 61,443 same-sex dizygotic… (More)
DOI: 10.1016/j.cgh.2016.12.041