Familial Mediterranean fever: the genetics of inflammation.

@article{Kastner1998FamilialMF,
  title={Familial Mediterranean fever: the genetics of inflammation.},
  author={Daniel L. Kastner},
  journal={Hospital practice},
  year={1998},
  volume={33 4},
  pages={131-4, 139-40, 143-6 passim}
}
When a patient complains of episodic fever accompanied by unexplained arthritis, peritonitis, pleurisy, or skin rash, this disorder should be considered. The disease-related gene codes for a protein that guides a neutrophil's participation in inflammation; the protein's existence implies an entire regulatory pathway hitherto unknown. At least two other mendelian periodic fever syndromes have also been described.