Familial Mediterranean fever: clinical, molecular and management advancements.

@article{Lidar2007FamilialMF,
  title={Familial Mediterranean fever: clinical, molecular and management advancements.},
  author={Merav Lidar and Avi Livneh},
  journal={The Netherlands journal of medicine},
  year={2007},
  volume={65 9},
  pages={318-24}
}
Familial Mediterranean fever (FMF), the most frequent of the periodic fever syndromes, is an autosomal recessive disease, predominantly affecting people of Mediterranean descent. The disease is caused by mutations in the MEFV gene, encoding the pyrin protein thought to be associated with the interleukin-1 related inflammation cascade. The condition manifests as attacks of serositis, commonly involving the abdomen, chest or joints, typically accompanied by fever and elevated acute phase… CONTINUE READING
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