Familial Mediterranean fever: clinical, molecular and management advancements.

  title={Familial Mediterranean fever: clinical, molecular and management advancements.},
  author={Merav Lidar and Avi Livneh},
  journal={The Netherlands journal of medicine},
  volume={65 9},
Familial Mediterranean fever (FMF), the most frequent of the periodic fever syndromes, is an autosomal recessive disease, predominantly affecting people of Mediterranean descent. The disease is caused by mutations in the MEFV gene, encoding the pyrin protein thought to be associated with the interleukin-1 related inflammation cascade. The condition manifests as attacks of serositis, commonly involving the abdomen, chest or joints, typically accompanied by fever and elevated acute phase… CONTINUE READING
81 Citations
56 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 81 extracted citations


Publications referenced by this paper.
Showing 1-10 of 56 references

3 year follow-up on a treatment for amyloid A (AA) amyloidosis: efficacy and safety of eprosidate (NC-503;1,3propanedisulfonate), the first of a new class of anti-amyloid compounds

  • PD HPGorevic, A Livneh
  • Arthritis Rheum
  • 2006

Similar Papers

Loading similar papers…